Blisters are a big deal! I have made the mistake of thinking otherwise but, blisters can impede the ability to train and participate in athletic adventures as much as an injury or illness. My advice is to take blisters seriously especially of you feeling one heating up under foot.
Here are a few of my go-to treatments and prevention tools:
When have blisters bust: https://www.amazon.com/Spenco-Skin-Blister-Sports-Count/dp/B004UOTUXK/ref=sr_1_8_a_it?ie=UTF8&qid=1493240870&sr=8-8&keywords=blister+pads I used this and made it through Ragnar Trail Relays with blisters that had popped before the event even started. I also added these where needed https://www.amazon.com/Band-Aid-Advanced-Protection-Adhesive-Bandages/dp/B000Y8W50G/ref=sr_1_4_a_it?ie=UTF8&qid=1493244021&sr=8-4&keywords=blister%2Bprevention&th=1
Super awesome for blister prevention that I use to reduce friction on new shoes and with my orthotics is this ease, simple solution https://www.amazon.com/Blister-Prevention-Patches-Runners-Athletes/dp/B003URZNW0/ref=sr_1_6_a_it?ie=UTF8&qid=1493243976&sr=8-6&keywords=blister+prevention